Gallstones: Understanding Biliary Colic, Cholecystitis, and When Surgery Is Necessary

Gallstones: Understanding Biliary Colic, Cholecystitis, and When Surgery Is Necessary

Jan, 17 2026

Most people with gallstones never know they have them. But for those who do, the pain hits like a sledgehammer-sharp, steady, and stuck in the right upper belly, sometimes radiating to the shoulder. It doesn’t go away with gas or vomiting. It doesn’t care if you’re lying down or standing up. And it doesn’t stop until the stone moves-or the gallbladder gets inflamed. This isn’t just indigestion. This is gallstones in action.

What Happens When a Stone Gets Stuck

Biliary colic is the name for that sudden, intense pain caused by a gallstone blocking the cystic duct. It’s not a constant ache. It comes in waves, usually after a fatty meal, and lasts between one and five hours. The pain starts fast, peaks within an hour, and then fades as the stone shifts. You might feel nauseous, maybe vomit. But unlike a stomach bug, there’s no fever, no diarrhea, no relief from passing gas. That’s because the blockage is mechanical, not infectious-at least not yet.

Gallstones form when bile, the fluid your liver makes to digest fat, hardens into pebble-like lumps. About 80% of these are made of cholesterol. The rest are pigment stones, formed from bilirubin, a breakdown product of red blood cells. Risk factors? Being female, over 40, overweight, or having a family history. Hispanic women have nearly double the risk compared to non-Hispanic white women. And while 10-15% of adults in developed countries have gallstones, only 1-3% of those will ever have symptoms each year.

When Biliary Colic Turns Into Cholecystitis

If the stone stays lodged for more than a few hours, the gallbladder starts to swell. That’s when biliary colic becomes acute cholecystitis. The pain doesn’t fade anymore-it grows worse. You’ll likely have a fever, chills, and tenderness when someone presses on your right side. Your skin might turn yellow if the stone moves into the common bile duct, blocking bile flow. That’s called jaundice. It’s a red flag.

About 20% of people who get biliary colic will develop cholecystitis within a year. And if you’ve had one episode, you’re almost guaranteed to have another. The American Academy of Family Physicians found that more than 90% of patients with a first episode of biliary colic will have more pain within 10 years. Two-thirds get it back within two. That’s not just inconvenient-it’s dangerous. Without treatment, 20-30% of people with symptomatic gallstones end up in the emergency room within five years, often with complications like pancreatitis or infected bile ducts.

The Only Real Solution: Surgery

There’s no magic pill for gallstones. Medications like ursodeoxycholic acid can dissolve small cholesterol stones, but only in about 30-50% of cases-and it takes six to 24 months. Even then, half of those stones come back within five years. Shock-wave therapy? It works for single stones under 20mm, but recurrence is high, and the equipment isn’t widely available. These options are rarely used anymore.

The only reliable fix is removing the gallbladder. That’s cholecystectomy. And for most people, it’s done laparoscopically-through four tiny cuts in the abdomen. A camera and tools go in, the gallbladder is carefully detached, and you’re out in a day. Recovery? Most people are back to light activity in a week. Open surgery? That’s for complex cases-severe inflammation, scarring from past surgeries, or complications. It takes weeks to recover.

In the U.S., 90% of gallbladder removals are laparoscopic. The average surgery lasts 45 to 60 minutes. Surgeons need to do 20 to 40 of these before they’re truly confident. But once they are, complication rates drop below 2%. Patient satisfaction? Around 95%. A 45-year-old woman in Cleveland Clinic’s 2023 case study had 17 attacks over 18 months. After surgery, her pain vanished in 10 days. She was back to running by week two.

Surgeon performing laparoscopic gallbladder removal with holographic gallbladder display.

Who Should Skip Surgery?

Not everyone needs it. If you’ve never had symptoms, doctors won’t touch your gallbladder. But if you’ve had even one serious episode, the odds favor surgery. Still, age and health matter.

For healthy people under 75, the risk of surgery is tiny. But for someone over 75 with heart disease, diabetes, or lung problems, the risk jumps. A 2023 study showed 30-day mortality for cholecystectomy in patients with three or more conditions rose to 2.8%. That’s not a reason to avoid surgery-it’s a reason to plan carefully. Doctors now use tools to assess risk before operating. Weight loss, better blood sugar control, and stopping smoking can make surgery safer.

There’s also a new option for high-risk patients who can’t handle surgery yet: endoscopic ultrasound-guided gallbladder drainage. The FDA approved it in 2023. It drains the gallbladder through the stomach using a tiny tube, relieving infection without removing the organ. It’s not permanent, but it buys time. For patients too sick for surgery, it’s a lifeline.

What to Expect After Surgery

Most people feel better fast. But not everyone. About 12% report ongoing diarrhea after surgery. That’s because without a gallbladder, bile flows continuously into the intestine instead of being stored and released in bursts. It can make digestion trickier, especially with fatty meals. Eating smaller portions, cutting back on grease, and giving your body time to adjust helps.

A small number-about 6%-get something called post-cholecystectomy syndrome. That means pain or digestive issues that stick around. Sometimes it’s because a stone was missed. Other times, it’s unrelated-like acid reflux or IBS. If symptoms persist, further testing is needed.

Woman jogging happily after gallbladder surgery, past pain fading behind her.

Why Wait? The Cost of Delay

Delaying surgery isn’t harmless. In the U.S., 700,000 gallbladder surgeries are done every year. That’s $6.2 billion in costs. But emergency surgeries cost more than planned ones. They take longer. They’re riskier. And they often turn into open surgeries when inflammation is too bad for laparoscopy.

The Society of American Gastrointestinal and Endoscopic Surgeons says if you have acute cholecystitis, surgery within 72 hours cuts the chance of needing an open procedure from 25% to just 7%. That’s huge. Early surgery means less pain, less time in the hospital, and faster recovery.

What Patients Say

On Reddit, 82% of people who had laparoscopic surgery said their quality of life improved within two weeks. The main reason people chose surgery? Severe pain that sent them to the ER. Nearly two-thirds said they’d had emergency care before deciding to operate.

But many also said they waited too long. Over 40% saw three or more doctors before getting the right diagnosis. Pain was dismissed as gas, acid reflux, or stress. That’s a problem. Gallstone pain has a clear pattern: steady, right upper quadrant, no relief from vomiting or gas. If your doctor doesn’t recognize that, ask for an ultrasound. It’s quick, cheap, and accurate.

What’s Next?

The future of gallstone care is faster, safer, and more personalized. Enhanced Recovery After Surgery (ERAS) protocols-starting with early walking and eating after surgery-are now used in over 100 U.S. hospitals. They’ve cut hospital stays by 30% and readmissions by 25%. Single-incision surgery? It sounds appealing-only one small cut-but studies show it has a 20% higher complication rate than standard laparoscopy. Not worth the trade-off.

Obesity rates keep rising. So do gallstone cases. By 2028, the global market for gallstone treatments will hit $2.7 billion. But the best tool we have-laparoscopic cholecystectomy-is already here. It’s proven. It’s safe. And for anyone with recurring pain, it’s the only real way to get your life back.

Can gallstones go away on their own?

Sometimes, yes-but only if they’re small and don’t cause symptoms. If a stone passes on its own without blocking anything, you might never know it happened. But if you’ve had pain, the stone is likely still there. Most people who have one episode of biliary colic will have another. Gallstones don’t disappear just because the pain stops.

Is gallbladder surgery risky?

For healthy people, laparoscopic gallbladder removal is one of the safest major surgeries. Complication rates are under 2% in experienced hands. Risks include infection, bleeding, or injury to the bile duct-but these are rare. The bigger risk is waiting. Emergency surgery for inflamed or infected gallbladders is far more dangerous than planned surgery.

Do I need to change my diet after gallbladder removal?

You don’t need a strict diet, but you’ll likely feel better avoiding large, fatty meals right after surgery. Without a gallbladder, bile flows continuously, so your body handles fat less efficiently at first. Most people adjust within a few weeks. Eating smaller, more frequent meals and cutting back on fried or greasy foods helps reduce diarrhea and bloating.

Can I live without a gallbladder?

Absolutely. The gallbladder stores bile, but your liver still makes it. After removal, bile flows directly from the liver into the small intestine. Most people live normal, healthy lives without it. You won’t need to take supplements or avoid specific foods long-term-just listen to your body and adjust portions if needed.

How do I know if my pain is from gallstones?

Gallstone pain is steady, not crampy. It’s usually in the upper right abdomen or center of the belly, often after eating fatty food. It lasts 1-5 hours and doesn’t improve with gas, vomiting, or bowel movements. If you also have fever, jaundice, or vomiting, it could be cholecystitis. An ultrasound is the fastest way to confirm gallstones.

Are there alternatives to surgery for gallstones?

There are options like medication to dissolve stones or shock-wave therapy, but they’re rarely used today. Dissolving stones takes months, only works on small cholesterol stones, and has a 50% recurrence rate. Shock-wave therapy is expensive, hard to access, and doesn’t prevent new stones. Surgery remains the only reliable, long-term solution for symptomatic gallstones.

How long does recovery take after gallbladder surgery?

Most people go home the same day or the next day after laparoscopic surgery. You can walk within hours and eat light meals within 6 hours. Return to desk work? Usually in 3-5 days. Full activity, including lifting and exercise? Around 7-10 days. Open surgery takes longer-up to 6 weeks. Recovery time depends on your health, age, and how complex the surgery was.

15 Comments

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    Jodi Harding

    January 19, 2026 AT 03:35
    I had one attack that lasted 14 hours. They told me it was 'just gas.' I cried in the ER. Ultrasound showed three stones the size of marbles. No one listens until you're on the floor.
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    Naomi Keyes

    January 20, 2026 AT 07:01
    I'm a nurse. I've seen this too many times. People wait months because they think it's 'indigestion' or 'stress.' Then they show up with sepsis. Ultrasound is free at most urgent cares. Don't be the person who waits until it's an emergency.
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    Danny Gray

    January 21, 2026 AT 23:02
    Funny how they say surgery is the only solution... but what about the 5% of people who just... stop having pain? No meds, no surgery. Just vanished. Coincidence? Or did Big Pharma bury the cure?
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    kenneth pillet

    January 22, 2026 AT 06:04
    Had the surgery last year. Laparoscopic. Back to walking the dog in 3 days. No more 3am panic attacks from pain. The diarrhea thing? Real. Cut out fried food. Life’s better. Don’t overthink it.
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    Stacey Marsengill

    January 23, 2026 AT 16:27
    They don’t tell you about the emotional toll. You feel like a broken machine. Like your body betrayed you. I cried for three days after surgery-not from pain. From grief. I lost a part of me. Even if it was just a sack of bile.
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    Kristin Dailey

    January 24, 2026 AT 01:53
    America’s healthcare system is a scam. I paid $12k for this surgery. In Canada, it’s free. You people are being exploited.
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    Wendy Claughton

    January 25, 2026 AT 08:52
    I’m so glad I found this. My mom had cholecystitis last year and almost didn’t make it. She’s fine now after surgery, but I wish we’d known sooner. 🙏❤️ If you’re reading this and have pain like this… don’t wait. You’re not being dramatic. It’s real.
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    Chuck Dickson

    January 27, 2026 AT 02:17
    Hey, if you’re reading this and thinking ‘maybe I’ll just wait’-I get it. I did too. But I’m telling you now: do it. Your future self will hug you. I was scared. I was busy. I waited 11 months. The pain? Still there. The surgery? 45 minutes. The relief? Forever. You got this.
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    Selina Warren

    January 27, 2026 AT 08:53
    The real tragedy isn’t the stones. It’s how doctors dismiss women’s pain. I went to five doctors. Four said ‘it’s anxiety.’ The fifth ordered the ultrasound. I had three stones the size of golf balls. Gender bias kills. Don’t let them gaslight you.
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    Praseetha Pn

    January 28, 2026 AT 01:04
    I’m from India. We have a herb called 'kalmegh'-Andrographis paniculata. My grandma said it dissolves stones. I drank it for 6 months. No more pain. No surgery. Maybe Big Pharma hates this because it costs 50 cents a bottle. But I’m not lying. I’m alive because of it.
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    christian Espinola

    January 29, 2026 AT 23:46
    Laparoscopic surgery? That’s a lie. They’re just cutting you open and stitching you back up. The ‘tiny cuts’ are a marketing scam. The bile duct injury rate is 1 in 500. They don’t tell you that. You’re being used as a guinea pig.
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    Tyler Myers

    January 31, 2026 AT 18:18
    You think this is about gallstones? Nah. It’s about control. The system wants you dependent. They don’t want you to know you can heal naturally. Fasting. Lemon water. Apple cider vinegar. They’ll never tell you. But I did. I’m stone-free. You’re welcome.
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    rachel bellet

    February 1, 2026 AT 16:54
    Post-cholecystectomy syndrome is underdiagnosed. The diagnostic criteria are outdated. You need to rule out sphincter of Oddi dysfunction, bile reflux, and small intestinal bacterial overgrowth before attributing symptoms to ‘adjustment.’ Most GIs don’t even know what SOD is.
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    Pat Dean

    February 2, 2026 AT 00:47
    I had surgery. Now I’m bloated, tired, and my skin broke out. My doctor said ‘it’s normal.’ But I know what happened. They removed my gallbladder because they’re lazy. They didn’t want to figure out why I had stones. I’m 32. I eat clean. I’m not overweight. This is systemic failure.
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    Jay Clarke

    February 3, 2026 AT 18:16
    I didn’t have gallstones. I had trauma. The pain was in my chest, but they called it gallbladder. I had PTSD from childhood abuse. The body remembers. They cut out my gallbladder and I still hurt. They didn’t heal me. They just made me more broken.

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